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Supramolecular Glycosylation Accelerates Proteolytic Degradation of Peptide Nanofibrils

[Image: see text] Despite the recent consensus that the oligomers of amyloid peptides or aberrant proteins are cytotoxic species, there is still a need for an effective way to eliminate the oligomers. Based on the fact that normal proteins are more glycosylated than pathogenic proteins, we show that...

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Detalles Bibliográficos
Autores principales: Yuan, Dan, Shi, Junfeng, Du, Xuewen, Zhou, Ning, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941208/
https://www.ncbi.nlm.nih.gov/pubmed/26237170
http://dx.doi.org/10.1021/jacs.5b05888