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Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions

The emergence of vascular disrupting agents (VDAs) is a significant advance in the treatment of solid tumors. VDAs induce rapid and selective shutdown of tumor blood flow resulting in massive necrosis. However, a viable marginal tumor rim always remains after VDA treatment and is a major cause of re...

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Detalles Bibliográficos
Autores principales: Liang, Wenjie, Ni, Yicheng, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941252/
https://www.ncbi.nlm.nih.gov/pubmed/26812886
http://dx.doi.org/10.18632/oncotarget.6999