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Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes

Chromatin disorganization is one of the major alterations linked to prelamin A processing impairment. In this study we demonstrate that BAF is necessary to modulate prelamin A effects on chromatin structure. We show that when prelamin A and BAF cannot properly interact no prelamin A-dependent effect...

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Detalles Bibliográficos
Autores principales: Loi, Manuela, Cenni, Vittoria, Duchi, Serena, Squarzoni, Stefano, Lopez-Otin, Carlos, Foisner, Roland, Lattanzi, Giovanna, Capanni, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941268/
https://www.ncbi.nlm.nih.gov/pubmed/26701887
http://dx.doi.org/10.18632/oncotarget.6697