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Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes
Chromatin disorganization is one of the major alterations linked to prelamin A processing impairment. In this study we demonstrate that BAF is necessary to modulate prelamin A effects on chromatin structure. We show that when prelamin A and BAF cannot properly interact no prelamin A-dependent effect...
Autores principales: | Loi, Manuela, Cenni, Vittoria, Duchi, Serena, Squarzoni, Stefano, Lopez-Otin, Carlos, Foisner, Roland, Lattanzi, Giovanna, Capanni, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941268/ https://www.ncbi.nlm.nih.gov/pubmed/26701887 http://dx.doi.org/10.18632/oncotarget.6697 |
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