Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells

Deciding appropriate therapy for multiple myeloma (MM) is challenging because of the occurrence of multiple chromosomal changes and the fatal nature of the disease. In the current study, gamabufotalin (GBT) was isolated from toad venom, and its tumor-specific cytotoxicity was investigated in human M...

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Detalles Bibliográficos
Autores principales: Yu, Zhenlong, Li, Tao, Wang, Chao, Deng, Sa, Zhang, Baojing, Huo, Xiaokui, Zhang, Bo, Wang, Xiaobo, Zhong, Yuping, Ma, Xiaochi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941272/
https://www.ncbi.nlm.nih.gov/pubmed/26894970
http://dx.doi.org/10.18632/oncotarget.7398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941272/
https://www.ncbi.nlm.nih.gov/pubmed/26894970
http://dx.doi.org/10.18632/oncotarget.7398

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