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Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common extracranial solid tumor of childhood. We and others have identified distinct patterns of genomic change that underlie diverse clinical behaviors, from spontaneous regression to relentless progression. We first identif...

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Detalles Bibliográficos
Autores principales: Naraparaju, Koumudi, Kolla, Venkatadri, Zhuang, Tiangang, Higashi, Mayumi, Iyer, Radhika, Kolla, Sriharsha, Okawa, Erin R., Blobel, Gerd A., Brodeur, Garrett M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941291/
https://www.ncbi.nlm.nih.gov/pubmed/26895110
http://dx.doi.org/10.18632/oncotarget.7434