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Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation

Podoplanin (PDPN) is a transmembrane glycoprotein that plays crucial roles in embryonic development, the immune response, and malignant progression. Here, we report that cells ectopically or endogenously expressing PDPN release extracellular vesicles (EVs) that contain PDPN mRNA and protein. PDPN in...

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Detalles Bibliográficos
Autores principales: Carrasco-Ramírez, Patricia, Greening, David W., Andrés, Germán, Gopal, Shashi K., Martín-Villar, Ester, Renart, Jaime, Simpson, Richard J., Quintanilla, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941298/
https://www.ncbi.nlm.nih.gov/pubmed/26893367
http://dx.doi.org/10.18632/oncotarget.7445