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Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation
Podoplanin (PDPN) is a transmembrane glycoprotein that plays crucial roles in embryonic development, the immune response, and malignant progression. Here, we report that cells ectopically or endogenously expressing PDPN release extracellular vesicles (EVs) that contain PDPN mRNA and protein. PDPN in...
Autores principales: | Carrasco-Ramírez, Patricia, Greening, David W., Andrés, Germán, Gopal, Shashi K., Martín-Villar, Ester, Renart, Jaime, Simpson, Richard J., Quintanilla, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941298/ https://www.ncbi.nlm.nih.gov/pubmed/26893367 http://dx.doi.org/10.18632/oncotarget.7445 |
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