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miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation

The long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been recently shown to be dysregulated in several cancers. However, the mechanisms underlying the role of MALAT1 in breast cancer remain unclear. Herein, we showed that MALAT1 was aberrantly increase...

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Detalles Bibliográficos
Autores principales: Feng, Tongbao, Shao, Fang, Wu, Qiyong, Zhang, Xiaohang, Xu, Dongqin, Qian, Keqing, Xie, Yewen, Wang, Shizhong, Xu, Ning, Wang, Yong, Qi, Chunjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941308/
https://www.ncbi.nlm.nih.gov/pubmed/26918449
http://dx.doi.org/10.18632/oncotarget.7578