Cargando…

Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop

A number of ribosomal proteins (RPs) have been shown to play a critical role in coordinating ribosome biogenesis with cell growth and proliferation by suppressing MDM2 to induce p53 activation. While how the MDM2-p53 pathway is regulated by multiple RPs is unclear, it remains to be interesting to id...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Xia, Li, Yuhuang, Dai, Mu-Shui, Sun, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941309/
https://www.ncbi.nlm.nih.gov/pubmed/26908445
http://dx.doi.org/10.18632/oncotarget.7479