Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

Cancer cells are subjected to fluid shear stress during passage through the venous and lymphatic system. Caveolin-1 (Cav-1), a principal structural component of caveolar membrane domains, contributes to cancer development but its mechanobiological roles under low shear stress (LSS) conditions remain...

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Detalles Bibliográficos
Autores principales: Yang, Hong, Guan, Liuyuan, Li, Shun, Jiang, Ying, Xiong, Niya, Li, Li, Wu, Chunhui, Zeng, Hongjuan, Liu, Yiyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941310/
https://www.ncbi.nlm.nih.gov/pubmed/26919102
http://dx.doi.org/10.18632/oncotarget.7583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941310/
https://www.ncbi.nlm.nih.gov/pubmed/26919102
http://dx.doi.org/10.18632/oncotarget.7583

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