Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis

As a natural health supplement, 3,3′-diindolylmethane (DIM) is proposed as a preventive and chemotherapeutic agent for cancer by inhibiting cell proliferation and inducing cell apoptosis. However, we found that in contrary to high level of DIM (30 μM), low level of DIM (1 μM and 10 μM) obviously pro...

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Detalles Bibliográficos
Autores principales: Zhu, Yanhua, Zhang, Bin, Gong, Aihua, Fu, Hailong, Zhang, Xu, Shi, Hui, Sun, Yaoxiang, Wu, Lijun, Pan, Zhaoji, Mao, Fei, Zhu, Wei, Qian, Hui, Xu, Wenrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941316/
https://www.ncbi.nlm.nih.gov/pubmed/26918831
http://dx.doi.org/10.18632/oncotarget.7684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941316/
https://www.ncbi.nlm.nih.gov/pubmed/26918831
http://dx.doi.org/10.18632/oncotarget.7684

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