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Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis
As a natural health supplement, 3,3′-diindolylmethane (DIM) is proposed as a preventive and chemotherapeutic agent for cancer by inhibiting cell proliferation and inducing cell apoptosis. However, we found that in contrary to high level of DIM (30 μM), low level of DIM (1 μM and 10 μM) obviously pro...
Autores principales: | Zhu, Yanhua, Zhang, Bin, Gong, Aihua, Fu, Hailong, Zhang, Xu, Shi, Hui, Sun, Yaoxiang, Wu, Lijun, Pan, Zhaoji, Mao, Fei, Zhu, Wei, Qian, Hui, Xu, Wenrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941316/ https://www.ncbi.nlm.nih.gov/pubmed/26918831 http://dx.doi.org/10.18632/oncotarget.7684 |
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