p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

p85α is a regulatory subunit of phosphatidylinositol 3-kinase (PI3K) that is a key lipid enzyme for generating phosphatidylinositol 3, 4, 5-trisphosphate, and subsequently activates signaling that ultimately regulates cell cycle progression, cell growth, cytoskeletal changes, and cell migration. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Qipeng, Guo, Xirui, Gu, Jiayan, Zhang, Liping, Jin, Honglei, Huang, Haishan, Li, Jingxia, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941340/
https://www.ncbi.nlm.nih.gov/pubmed/26918608
http://dx.doi.org/10.18632/oncotarget.7674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941340/
https://www.ncbi.nlm.nih.gov/pubmed/26918608
http://dx.doi.org/10.18632/oncotarget.7674

Ejemplares similares