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p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

p85α is a regulatory subunit of phosphatidylinositol 3-kinase (PI3K) that is a key lipid enzyme for generating phosphatidylinositol 3, 4, 5-trisphosphate, and subsequently activates signaling that ultimately regulates cell cycle progression, cell growth, cytoskeletal changes, and cell migration. In...

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Detalles Bibliográficos
Autores principales:	Xie, Qipeng, Guo, Xirui, Gu, Jiayan, Zhang, Liping, Jin, Honglei, Huang, Haishan, Li, Jingxia, Huang, Chuanshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941340/ https://www.ncbi.nlm.nih.gov/pubmed/26918608 http://dx.doi.org/10.18632/oncotarget.7674

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