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Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer

The Tid1 protein is a DnaJ co-chaperone that has two alternative splicing isoforms: Tid1 long form (Tid1-L) and Tid1 short form (Tid1-S). Recent studies have shown that Tid1-L functions as a tumor suppressor by decreasing EGFR signaling in various cancers, including head and neck cancer and non-smal...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Yuan, Jan, Chia-Ing, Pi, Wen-Chieh, Wang, Wen-Lung, Yang, Pan-Chyr, Wang, Tong-Hong, Karni, Rotem, Wang, Tzu-Chien V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941349/
https://www.ncbi.nlm.nih.gov/pubmed/26919236
http://dx.doi.org/10.18632/oncotarget.7606