ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

Understanding mast cell development is essential due to their critical role in regulating immunity and autoimmune diseases. Here, we show how Rho kinases (ROCK) regulate mast cell development and can function as therapeutic targets for treating allergic diseases. Rock1 deficiency results in delayed...

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Detalles Bibliográficos
Autores principales: Kapur, Reuben, Shi, Jianjian, Ghosh, Joydeep, Munugalavadla, Veerendra, Sims, Emily, Martin, Holly, Wei, Lei, Mali, Raghuveer Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941361/
https://www.ncbi.nlm.nih.gov/pubmed/26943578
http://dx.doi.org/10.18632/oncotarget.7851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941361/
https://www.ncbi.nlm.nih.gov/pubmed/26943578
http://dx.doi.org/10.18632/oncotarget.7851

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