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ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells
Understanding mast cell development is essential due to their critical role in regulating immunity and autoimmune diseases. Here, we show how Rho kinases (ROCK) regulate mast cell development and can function as therapeutic targets for treating allergic diseases. Rock1 deficiency results in delayed...
Autores principales: | Kapur, Reuben, Shi, Jianjian, Ghosh, Joydeep, Munugalavadla, Veerendra, Sims, Emily, Martin, Holly, Wei, Lei, Mali, Raghuveer Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941361/ https://www.ncbi.nlm.nih.gov/pubmed/26943578 http://dx.doi.org/10.18632/oncotarget.7851 |
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