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High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

Prostate cancer remains a deadly disease especially when patients become resistant to drugs that target the Androgen Receptor (AR) ligand binding domain. At this stage, patients develop recurring castrate-resistant prostate cancers (CRPCs). Interestingly, CRPC tumors maintain dependency on AR for gr...

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Detalles Bibliográficos
Autores principales: Stossi, Fabio, Dandekar, Radhika D., Bolt, Michael J., Newberg, Justin Y., Mancini, Maureen G., Kaushik, Akash K., Putluri, Vasanta, Sreekumar, Arun, Mancini, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941363/
https://www.ncbi.nlm.nih.gov/pubmed/26918604
http://dx.doi.org/10.18632/oncotarget.7655