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Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel

The potassium channel Kv 1.3 plays a vital part in the activation of T lymphocytes and is an attractive pharmacological target for autoimmune diseases. BmP02, a 28-residue peptide isolated from Chinese scorpion (Buthus martensi Karsch) venom, is a potent and selective Kv1.3 channel blocker. However,...

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Detalles Bibliográficos
Autores principales: Wu, B., Wu, B. F., Feng, Y. J., Tao, J., Ji, Y. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941521/
https://www.ncbi.nlm.nih.gov/pubmed/27403813
http://dx.doi.org/10.1038/srep29431