CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors

Serotonin 1a-receptor (5-HT1aR) has been specifically implicated in the pathogenesis of anxiety. However, the mechanism underlying the role of 5-HT1aR in anxiety remains poorly understood. Here we show in mice that the transcription factor cAMP response element binding protein (CREB) in the hippocam...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Cai, Cheng-Yun, Wu, Hai-Yin, Zhu, Li-Juan, Luo, Chun-Xia, Zhu, Dong-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941576/
https://www.ncbi.nlm.nih.gov/pubmed/27404655
http://dx.doi.org/10.1038/srep29551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941576/
https://www.ncbi.nlm.nih.gov/pubmed/27404655
http://dx.doi.org/10.1038/srep29551

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