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CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors
Serotonin 1a-receptor (5-HT1aR) has been specifically implicated in the pathogenesis of anxiety. However, the mechanism underlying the role of 5-HT1aR in anxiety remains poorly understood. Here we show in mice that the transcription factor cAMP response element binding protein (CREB) in the hippocam...
Autores principales: | Zhang, Jing, Cai, Cheng-Yun, Wu, Hai-Yin, Zhu, Li-Juan, Luo, Chun-Xia, Zhu, Dong-Ya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941576/ https://www.ncbi.nlm.nih.gov/pubmed/27404655 http://dx.doi.org/10.1038/srep29551 |
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