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LeftyA decreases Actin Polymerization and Stiffness in Human Endometrial Cancer Cells

LeftyA, a cytokine regulating stemness and embryonic differentiation, down-regulates cell proliferation and migration. Cell proliferation and motility require actin reorganization, which is under control of ras-related C3 botulinum toxin substrate 1 (Rac1) and p21 protein-activated kinase 1 (PAK1)....

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Detalles Bibliográficos
Autores principales: Salker, Madhuri S., Schierbaum, Nicolas, Alowayed, Nour, Singh, Yogesh, Mack, Andreas F., Stournaras, Christos, Schäffer, Tilman E., Lang, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941646/
https://www.ncbi.nlm.nih.gov/pubmed/27404958
http://dx.doi.org/10.1038/srep29370