A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease

APOE ε4 is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD) and accounts for 50–65% of late-onset AD. Late-onset AD patients carrying or not carrying APOE ε4 manifest many clinico-pathological distinctions. Thus, we applied a weighted gene co-expression network analysis to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Shan, Tang, Ling, Zhao, Na, Yang, Wanling, Qiu, Yu, Chen, Hong-Zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941795/
https://www.ncbi.nlm.nih.gov/pubmed/27462267
http://dx.doi.org/10.3389/fnagi.2016.00171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941795/
https://www.ncbi.nlm.nih.gov/pubmed/27462267
http://dx.doi.org/10.3389/fnagi.2016.00171

Ejemplares similares