Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells

Background  In case of influenza pandemic, a robust, easy and clean technique to prepare reassortants would be necessary. Objectives  Using reverse genetics, we prepared two vaccine reassortants (A/H5N1 × PR8 and A/H7N1 × PR8) exhibiting the envelope glycoproteins from non‐pathogenic avian viruses,...

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Detalles Bibliográficos
Autores principales: Legastelois, Isabelle, Garcia‐Sastre, Adolfo, Palese, Peter, Tumpey, Terrence M., Maines, Taronna R., Katz, Jacqueline M., Vogel, Frederick R., Moste, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941877/
https://www.ncbi.nlm.nih.gov/pubmed/19453414
http://dx.doi.org/10.1111/j.1750-2659.2007.00015.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941877/
https://www.ncbi.nlm.nih.gov/pubmed/19453414
http://dx.doi.org/10.1111/j.1750-2659.2007.00015.x

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