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Transcutaneous delivery and thermostability of a dry trivalent inactivated influenza vaccine patch

A patch containing a trivalent inactivated influenza vaccine (TIV) was prepared in a dried, stabilized formulation for transcutaneous delivery. When used in a guinea pig immunogenicity model, the dry patch was as effective as a wet TIV patch in inducing serum anti‐influenza IgG antibodies. When the...

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Detalles Bibliográficos
Autores principales: Frolov, Vladimir G., Seid, Robert C., Odutayo, Olabisi, Al‐Khalili, Mohammad, Yu, Jianmei, Frolova, Olga Y., Vu, Hong, Butler, Barbara A., Look, Jee Loon, Ellingsworth, Larry R., Glenn, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941894/
https://www.ncbi.nlm.nih.gov/pubmed/19453472
http://dx.doi.org/10.1111/j.1750-2659.2008.00040.x