Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications

Methylation of cytosine deoxynucleotides (dC(5m)) is a well-established epigenetic mark, but in higher eukaryotes much less is known about modifications affecting other deoxynucleotides. Here, we report the detection of N-6-methyl-deoxyadenosine (dA(6m)) in vertebrate DNA, specifically in Xenopus la...

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Detalles Bibliográficos
Autores principales: Koziol, Magdalena J., Bradshaw, Charles R., Allen, George E., Costa, Ana S.H., Frezza, Christian, Gurdon, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941928/
https://www.ncbi.nlm.nih.gov/pubmed/26689968
http://dx.doi.org/10.1038/nsmb.3145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941928/
https://www.ncbi.nlm.nih.gov/pubmed/26689968
http://dx.doi.org/10.1038/nsmb.3145

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