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AplusB: A Web Application for Investigating A + B Designs for Phase I Cancer Clinical Trials
In phase I cancer clinical trials, the maximum tolerated dose of a new drug is often found by a dose-escalation method known as the A + B design. We have developed an interactive web application, AplusB, which computes and returns exact operating characteristics of A + B trial designs. The applicati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942070/ https://www.ncbi.nlm.nih.gov/pubmed/27403961 http://dx.doi.org/10.1371/journal.pone.0159026 |