Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells

After infection with T. brucei AnTat 1.1, C57BL/6 mice lost splenic B2 B cells and lymphoid follicles, developed poor parasite-specific antibody responses, lost weight, became anemic and died with fulminating parasitemia within 35 days. In contrast, infected C57BL/6 mice lacking the cytotoxic granul...

Descripción completa

Detalles Bibliográficos
Autores principales: Frenkel, Deborah, Zhang, Fengqiu, Guirnalda, Patrick, Haynes, Carole, Bockstal, Viki, Radwanska, Magdalena, Magez, Stefan, Black, Samuel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942092/
https://www.ncbi.nlm.nih.gov/pubmed/27403737
http://dx.doi.org/10.1371/journal.ppat.1005733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942092/
https://www.ncbi.nlm.nih.gov/pubmed/27403737
http://dx.doi.org/10.1371/journal.ppat.1005733

Ejemplares similares