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Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells
After infection with T. brucei AnTat 1.1, C57BL/6 mice lost splenic B2 B cells and lymphoid follicles, developed poor parasite-specific antibody responses, lost weight, became anemic and died with fulminating parasitemia within 35 days. In contrast, infected C57BL/6 mice lacking the cytotoxic granul...
Autores principales: | Frenkel, Deborah, Zhang, Fengqiu, Guirnalda, Patrick, Haynes, Carole, Bockstal, Viki, Radwanska, Magdalena, Magez, Stefan, Black, Samuel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942092/ https://www.ncbi.nlm.nih.gov/pubmed/27403737 http://dx.doi.org/10.1371/journal.ppat.1005733 |
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