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Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens

Mammalian host response to pathogenic infections is controlled by a complex regulatory network connecting regulatory proteins such as transcription factors and signaling proteins to target genes. An important challenge in infectious disease research is to understand molecular similarities and differ...

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Detalles Bibliográficos
Autores principales: Chasman, Deborah, Walters, Kevin B., Lopes, Tiago J. S., Eisfeld, Amie J., Kawaoka, Yoshihiro, Roy, Sushmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942116/
https://www.ncbi.nlm.nih.gov/pubmed/27403523
http://dx.doi.org/10.1371/journal.pcbi.1005013