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Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation

Activation of inflammatory pathways represents a central mechanism in multiple disease states both acute and chronic. Triggered via either pathogen or tissue damage-associated molecular motifs, common biochemical pathways lead to conserved yet variable physiological and immunological alterations. Di...

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Detalles Bibliográficos
Autores principales: Fullerton, James N., Segre, Elisabetta, De Maeyer, Roel P.H., Maini, Alexander A.N., Gilroy, Derek W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942172/
https://www.ncbi.nlm.nih.gov/pubmed/27213711
http://dx.doi.org/10.3791/53913