A bioengineered niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy

A promising therapeutic strategy for diverse genetic disorders involves transplantation of autologous stem cells that have been genetically corrected ex vivo. A major challenge in such approaches is a loss of stem cell potency during stem cell culture. Here we describe a system for maintaining muscl...

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Detalles Bibliográficos
Autores principales: Quarta, Marco, Brett, Jamie O., DiMarco, Rebecca, De Morree, Antoine, Boutet, Stephane C., Chacon, Robert, Gibbons, Michael C., Garcia, Victor A., Su, James, Shrager, Joseph B., Heilshorn, Sarah, Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942359/
https://www.ncbi.nlm.nih.gov/pubmed/27240197
http://dx.doi.org/10.1038/nbt.3576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942359/
https://www.ncbi.nlm.nih.gov/pubmed/27240197
http://dx.doi.org/10.1038/nbt.3576

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