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A bioengineered niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy
A promising therapeutic strategy for diverse genetic disorders involves transplantation of autologous stem cells that have been genetically corrected ex vivo. A major challenge in such approaches is a loss of stem cell potency during stem cell culture. Here we describe a system for maintaining muscl...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942359/ https://www.ncbi.nlm.nih.gov/pubmed/27240197 http://dx.doi.org/10.1038/nbt.3576 |