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Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells

The influence of signals perceived by immature B cells during their development in bone marrow on their subsequent functions as mature cells are poorly defined. Here, we show that bone marrow cells transiently stimulated in vivo or in vitro through the Toll-like receptor 9 generate proB cells (CpG-p...

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Detalles Bibliográficos
Autores principales: Korniotis, Sarantis, Gras, Christophe, Letscher, Hélène, Montandon, Ruddy, Mégret, Jérôme, Siegert, Stefanie, Ezine, Sophie, Fallon, Padraic G., Luther, Sanjiv A., Fillatreau, Simon, Zavala, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942579/
https://www.ncbi.nlm.nih.gov/pubmed/27396388
http://dx.doi.org/10.1038/ncomms12134