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Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1

AU-rich element binding/degradation factor 1 (AUF1) plays a role in destabilizing mRNAs by forming complexes with AU-rich elements (ARE) in the 3′-untranslated regions. Multiple AUF1-ARE complexes regulate the translation of encoded products related to the cell cycle, apoptosis, and inflammation. AU...

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Detalles Bibliográficos
Autores principales: Choi, Young Jun, Yoon, Je-Hyun, Chang, Jeong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942602/
https://www.ncbi.nlm.nih.gov/pubmed/27437398
http://dx.doi.org/10.1155/2016/3286191