Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

To specifically target dendritic cells (DCs) to simultaneously express different therapeutic transgenes for inducing immune responses against tumors, we used a combined promoter system of adenoviral vectors. We selected a 216 bp short Hsp70B′ core promoter induced by a mutated, constitutively active...

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Detalles Bibliográficos
Autores principales: Knippertz, Ilka, Deinzer, Andrea, Dörrie, Jan, Schaft, Niels, Nettelbeck, Dirk M., Steinkasserer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942663/
https://www.ncbi.nlm.nih.gov/pubmed/27446966
http://dx.doi.org/10.1155/2016/6078473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942663/
https://www.ncbi.nlm.nih.gov/pubmed/27446966
http://dx.doi.org/10.1155/2016/6078473

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