Cargando…

Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

To specifically target dendritic cells (DCs) to simultaneously express different therapeutic transgenes for inducing immune responses against tumors, we used a combined promoter system of adenoviral vectors. We selected a 216 bp short Hsp70B′ core promoter induced by a mutated, constitutively active...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knippertz, Ilka, Deinzer, Andrea, Dörrie, Jan, Schaft, Niels, Nettelbeck, Dirk M., Steinkasserer, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942663/ https://www.ncbi.nlm.nih.gov/pubmed/27446966 http://dx.doi.org/10.1155/2016/6078473

Ejemplares similares

Breaking Entry-and Species Barriers: LentiBOOST(®) Plus Polybrene Enhances Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5
por: Strack, Astrid, et al.
Publicado: (2022)

BRAF and MEK Inhibitors Affect Dendritic-Cell Maturation and T-Cell Stimulation
por: Hoyer, Stefanie, et al.
Publicado: (2021)

Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells
por: Zinser, Elisabeth, et al.
Publicado: (2019)

Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells
por: Hoyer, Stefanie, et al.
Publicado: (2015)

Adenoviral Vector Vaccines Antigen Transgene
por: Ertl, Hildegund C.J.
Publicado: (2016)

Differential Modulation of Dendritic Cell Biology by Endogenous and Exogenous Aryl Hydrocarbon Receptor Ligands
por: Sadeghi Shermeh, Atefeh, et al.
Publicado: (2023)

Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update
por: Dörrie, Jan, et al.
Publicado: (2020)

A One-Armed Phase I Dose Escalation Trial Design: Personalized Vaccination with IKKβ-Matured, RNA-Loaded Dendritic Cells for Metastatic Uveal Melanoma
por: Koch, Elias A. T., et al.
Publicado: (2022)

Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization
por: Lai, Xin, et al.
Publicado: (2022)

Human Adenovirus-Specific γ/δ and CD8(+) T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation
por: Dörrie, Jan, et al.
Publicado: (2014)

Targeted adenoviral vectors
por: Vigne, E, et al.
Publicado: (2001)

Xenogenic Adenoviral Vectors
por: Mittal, Suresh K., et al.
Publicado: (2016)

Xenogenic Adenoviral Vectors
por: Both, Gerald W.
Publicado: (2002)

Cationic Liposome Conjugation to Recombinant Adenoviral Vector Reduces Viral Antigenicity
por: Natsume, Atsushi, et al.
Publicado: (2000)

ADENOVIRAL VECTORS FOR PROTEIN EXPRESSION
por: Von Seggern, Dan J., et al.
Publicado: (1999)

Construction and application of adenoviral vectors
por: Zhang, Hongbo, et al.
Publicado: (2023)

Editorial: Adenoviral Infection and Immunity, and Adenoviral Vectors for Gene Therapy Applications
por: Zhang, Qiwei, et al.
Publicado: (2022)

CARs: Beyond T Cells and T Cell-Derived Signaling Domains
por: Sievers, Nico M., et al.
Publicado: (2020)

CSPG4 as Target for CAR-T-Cell Therapy of Various Tumor Entities–Merits and Challenges
por: Harrer, Dennis C., et al.
Publicado: (2019)

CARs and Drugs: Pharmacological Ways of Boosting CAR-T-Cell Therapy
por: Harrer, Dennis Christoph, et al.
Publicado: (2023)

Adenoviral Vectors for Hemophilia Gene Therapy
por: Brunetti-Pierri, N, et al.
Publicado: (2013)

The Role of Chromatin in Adenoviral Vector Function
por: Wong, Carmen M., et al.
Publicado: (2013)

Use of adenoviral vectors as veterinary vaccines
por: Ferreira, T B, et al.
Publicado: (2005)

Immunology of Adenoviral Vectors in Cancer Therapy
por: Shaw, Amanda Rosewell, et al.
Publicado: (2019)

NF-κB activation triggers NK-cell stimulation by monocyte-derived dendritic cells
por: Bosch, Naomi C., et al.
Publicado: (2019)

Multivalent adenoviral vectors which use an antigen capsid-incorporation strategy for HIV vaccination
por: Gu, L, et al.
Publicado: (2012)

Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells
por: Hammer, Anna, et al.
Publicado: (2017)

T-Cell Responses in Merkel Cell Carcinoma: Implications for Improved Immune Checkpoint Blockade and Other Therapeutic Options
por: Gehrcken, Laura, et al.
Publicado: (2021)

Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen
por: Sheerin, Dylan, et al.
Publicado: (2021)

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors
por: López-Camacho, César, et al.
Publicado: (2018)

Adenoviral Vectors Stimulate Glucagon Transcription in Human Mesenchymal Stem Cells Expressing Pancreatic Transcription Factors
por: Zaldumbide, Arnaud, et al.
Publicado: (2012)

Using Multivalent Adenoviral Vectors for HIV Vaccination
por: Gu, Linlin, et al.
Publicado: (2013)

An Adenoviral Vector Based Vaccine for Rhodococcus equi
por: Giles, Carla, et al.
Publicado: (2016)

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
por: Ewer, Katie, et al.
Publicado: (2017)

Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors
por: Iampietro, M. Justin, et al.
Publicado: (2018)

Expanding the Spectrum of Adenoviral Vectors for Cancer Therapy
por: Gao, Jian, et al.
Publicado: (2020)

Targeted Adenoviral Vectors I: Transductional Targeting
por: Dmitriev, Igor P., et al.
Publicado: (2016)

Engineering Adenoviral Vectors with Improved GBM Selectivity
por: Bates, Emily A., et al.
Publicado: (2023)

Immunotherapy for Lewis lung carcinoma utilizing dendritic cells infected with CK19 gene recombinant adenoviral vectors
por: SUN, Q.F., et al.
Publicado: (2015)

CSPG4-Specific CAR T Cells for High-Risk Childhood B Cell Precursor Leukemia
por: Harrer, Dennis C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_br927g08336qtl60ger3lrncjk