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The Role of Interleukin-23 in the Early Development of Emphysema in HIV1(+) Smokers

Rationale. Matrix metalloproteinase-9 (MMP-9) expression is upregulated in alveolar macrophages (AM) of HIV1(+) smokers who develop emphysema. Knowing that lung epithelial lining fluid (ELF) of HIV1(+) smokers contains increased levels of inflammatory cytokines compared to HIV1(−) smokers, we hypoth...

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Detalles Bibliográficos
Autores principales: Barjaktarevic, Igor Z., Crystal, Ronald G., Kaner, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942665/
https://www.ncbi.nlm.nih.gov/pubmed/27446965
http://dx.doi.org/10.1155/2016/3463104