Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation

We investigated how mitochondrial membrane proteins remain soluble in the cytosol until their delivery to mitochondria or degradation at the proteasome. We show that Ubiquilin family proteins bind transmembrane domains in the cytosol to prevent aggregation and temporarily allow opportunities for mem...

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Detalles Bibliográficos
Autores principales: Itakura, Eisuke, Zavodszky, Eszter, Shao, Sichen, Wohlever, Matthew L., Keenan, Robert J., Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942676/
https://www.ncbi.nlm.nih.gov/pubmed/27345149
http://dx.doi.org/10.1016/j.molcel.2016.05.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942676/
https://www.ncbi.nlm.nih.gov/pubmed/27345149
http://dx.doi.org/10.1016/j.molcel.2016.05.020

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