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Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation
We investigated how mitochondrial membrane proteins remain soluble in the cytosol until their delivery to mitochondria or degradation at the proteasome. We show that Ubiquilin family proteins bind transmembrane domains in the cytosol to prevent aggregation and temporarily allow opportunities for mem...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942676/ https://www.ncbi.nlm.nih.gov/pubmed/27345149 http://dx.doi.org/10.1016/j.molcel.2016.05.020 |