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Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan

Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) are liver-specific autoimmune conditions that are characterized by chronic hepatic damage and often lead to cirrhosis and hepatic failure. Specifically, the protein tyrosine phosphatase N22 (PTPN22) gene encodes the lymphoid protein ty...

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Detalles Bibliográficos
Autores principales: Umemura, Takeji, Joshita, Satoru, Yamazaki, Tomoo, Komatsu, Michiharu, Katsuyama, Yoshihiko, Yoshizawa, Kaname, Tanaka, Eiji, Ota, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942688/
https://www.ncbi.nlm.nih.gov/pubmed/27406031
http://dx.doi.org/10.1038/srep29770