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A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis

Endogenous stress represents a major source of genome instability, but is in essence difficult to apprehend. Incorporation of labeled radionuclides into DNA constitutes a tractable model to analyze cellular responses to endogenous attacks. Here we show that incorporation of [(3)H]thymidine into CHO...

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Detalles Bibliográficos
Autores principales: Saintigny, Yannick, Chevalier, François, Bravard, Anne, Dardillac, Elodie, Laurent, David, Hem, Sonia, Dépagne, Jordane, Radicella, J. Pablo, Lopez, Bernard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942696/
https://www.ncbi.nlm.nih.gov/pubmed/27406380
http://dx.doi.org/10.1038/srep29412