Immunization Against Specific Fragments of Neurotrophin p75 Receptor Protects Forebrain Cholinergic Neurons in the Olfactory Bulbectomized Mice

Alzheimer’s disease (AD) is characterized by progressive cognitive impairment associated with marked cholinergic neuron loss and amyloid-β (Aβ) peptide accumulation in the brain. The cytotoxicity in AD is mediated, at least in part, by Aβ binding with the extracellular domain of the p75 neurotrophin...

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Detalles Bibliográficos
Autores principales: Bobkova, Natalia, Vorobyov, Vasily, Medvinskaya, Natalia, Nesterova, Inna, Tatarnikova, Olga, Nekrasov, Pavel, Samokhin, Alexander, Deev, Alexander, Sengpiel, Frank, Koroev, Dmitry, Volpina, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942728/
https://www.ncbi.nlm.nih.gov/pubmed/27163825
http://dx.doi.org/10.3233/JAD-160146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942728/
https://www.ncbi.nlm.nih.gov/pubmed/27163825
http://dx.doi.org/10.3233/JAD-160146

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