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A Longitudinal Motor Characterisation of the Hdh(Q111) Mouse Model of Huntington’s Disease
Background: Huntington’s disease (HD) is a rare, incurable neurodegenerative disorder caused by a CAG trinucleotide expansion with the first exon of the huntingtin gene. Numerous knock-in mouse models are currently available for modelling HD. However, before their use in scientific research, these m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942729/ https://www.ncbi.nlm.nih.gov/pubmed/27258586 http://dx.doi.org/10.3233/JHD-160191 |