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A Longitudinal Motor Characterisation of the Hdh(Q111) Mouse Model of Huntington’s Disease

Background: Huntington’s disease (HD) is a rare, incurable neurodegenerative disorder caused by a CAG trinucleotide expansion with the first exon of the huntingtin gene. Numerous knock-in mouse models are currently available for modelling HD. However, before their use in scientific research, these m...

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Detalles Bibliográficos
Autores principales:	Yhnell, Emma, Dunnett, Stephen B., Brooks, Simon P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2016
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942729/ https://www.ncbi.nlm.nih.gov/pubmed/27258586 http://dx.doi.org/10.3233/JHD-160191

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