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Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages

Mer signaling increases the transcriptional activity of liver X receptor (LXR) to promote the resolution of acute sterile inflammation. Here, we aimed to understand the pathway downstream of Mer signaling after growth arrest-specific protein 6 (Gas6) treatment that leads to LXR expression and transc...

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Detalles Bibliográficos
Autores principales: Kim, Si-Yoon, Lim, Eun-Jin, Yoon, Young-So, Ahn, Young-Ho, Park, Eun-Mi, Kim, Hee-Sun, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942780/
https://www.ncbi.nlm.nih.gov/pubmed/27406916
http://dx.doi.org/10.1038/srep29673