Therapeutic targeting of myeloid-derived suppressor cells involves a novel mechanism mediated by clusterin

Myeloid-derived suppressor cells (MDSCs) constitute a key checkpoint that impedes tumor immunity against cancer. Chemotherapeutic intervention of MDSCs has gained ground as a strategy for cancer therapy but its mechanism remains obscure.We report here a unique mechanism by which monocytic (M)-MDSCs...

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Detalles Bibliográficos
Autores principales: Zhou, Junmin, Donatelli, Sarah S., Gilvary, Danielle L., Tejera, Melba M., Eksioglu, Erika A., Chen, Xianghong, Coppola, Domenico, Wei, Sheng, Djeu, Julie Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942787/
https://www.ncbi.nlm.nih.gov/pubmed/27405665
http://dx.doi.org/10.1038/srep29521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942787/
https://www.ncbi.nlm.nih.gov/pubmed/27405665
http://dx.doi.org/10.1038/srep29521

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