Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity

Cell surface proteolysis is an integral yet poorly understood physiological process. The present study has examined how the pericellular collagenase membrane-type 1 matrix metalloproteinase (MT1-MMP) and membrane-mimicking environments interplay in substrate binding and processing. NMR derived struc...

Descripción completa

Detalles Bibliográficos
Autores principales: Cerofolini, Linda, Amar, Sabrina, Lauer, Janelle L., Martelli, Tommaso, Fragai, Marco, Luchinat, Claudio, Fields, Gregg B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942797/
https://www.ncbi.nlm.nih.gov/pubmed/27405411
http://dx.doi.org/10.1038/srep29511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942797/
https://www.ncbi.nlm.nih.gov/pubmed/27405411
http://dx.doi.org/10.1038/srep29511

Ejemplares similares