Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling

Rotavirus infection is associated with childhood progression to type 1 diabetes. Infection by monkey rotavirus RRV accelerates diabetes onset in non-obese diabetic (NOD) mice, which relates to regional lymph node infection and a T helper 1-specific immune response. When stimulated ex vivo with RRV,...

Descripción completa

Detalles Bibliográficos
Autores principales: Pane, Jessica A., Fleming, Fiona E., Graham, Kate L., Thomas, Helen E., Kay, Thomas W. H., Coulson, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942798/
https://www.ncbi.nlm.nih.gov/pubmed/27405244
http://dx.doi.org/10.1038/srep29697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942798/
https://www.ncbi.nlm.nih.gov/pubmed/27405244
http://dx.doi.org/10.1038/srep29697

Ejemplares similares